diff --git a/CMakeLists.txt b/CMakeLists.txt
index 56d1d512f5..381a0ca3a1 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -2766,8 +2766,6 @@ elseif(PSP)
   )
 
 elseif(PS2)
-  sdl_compile_definitions(PRIVATE "PS2" "__PS2__")
-
   sdl_glob_sources("${SDL3_SOURCE_DIR}/src/main/ps2/*.c")
 
   if(SDL_AUDIO)